AES Antikörper (AA 21-120)

Produktnummer ABIN1714012

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch AES in ELISA, ICC, IF (cc), IF (p), IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für AES Antikörper (AA 21-120) (ABIN1714012)

Target: AES (Amino-terminal Enhancer of Split (AES))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AES Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-AES Antikörper

Bindungsspezifität: AA 21-120

Homologie: Human,Mouse,Rat,Cow,Sheep,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TLE5/Amino-terminal enhancer of split

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu AES

Target: AES (Amino-terminal Enhancer of Split (AES))

Andere Bezeichnung: TLE5/Amino-terminal enhancer of split

Hintergrund:

Synonyms: Aes 1, Amino-terminal enhancer of split , Aes 2, aes, AES_HUMAN, Aes1, Aes2, Amino Enhancer of Split, Amino terminal enhancer of split, Amino-terminal enhancer of split, Esp 1, Esp1, Gp130 associated protein GAM, Gp130-associated protein GAM, GRG 5, GRG, GRG protein, GRG5, Protein ESP 1, Protein ESP1, Protein GRG, TLE 5, TLE5.

Background: TLE5 is a 197 amino acid nuclear protein that belongs to the TLE family. Expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle, TLE5 functions as either a homooligomer or a heterooligomer with other TLE family members and, through this association, dominantly represses the expression of TLE genes. In addition, TLE5 can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events. Two isoforms of TLE5 exist due to alternative splicing events.

Gen-ID: 166

Pathways: WNT Signalweg, SARS-CoV-2 Protein Interaktom